Skip to main content

View full-text article in PMC

. 2019 Aug 28;11(16):6569–6583. doi: 10.18632/aging.102211

Table 7. The relationship between ADAMTS7 rs3825807 variant and IS stratified by TOAST classification in combined IS patients.

	ADAMTS7 rs3825807
	Genotype			P value^a	Allele		P value^a	OR (95% CI)
	AA	AG	GG	P value^a	A	G	P value^a	OR (95% CI)
Control (n=1268)	855(67.4)	368(29.0)	45(3.6)		2078(81.9)	458(18.1)
Cases
LAA (n=812)	607(74.8)	189(23.3)	16(2.0)	0.0033	1403(86.4)	221(13.6)	6.0×10^-4	0.72(0.60-0.85)
SAA (n=355)	258(72.7)	88 (24.8)	9(2.5)	0.23	604 (85.1)	106(14.9)	0.069	0.80(0.63- 1.00)
CE (n=46)	36(78.3)	9(19.6)	1(2.2)	0.32	81(88.0)	11(12.0)	0.13	0.62(0.33- 1.17)
UE (n=66)	53(80.3)	12(18.2)	1(1.5)	0.19	118(89.4)	14(10.6)	0.058	0.54(0.31-0.95)

LAA: Large-artery atherosclerosis; SAA: Small-artery atherosclerosis; CE: Cardioembolic; UE: Undetermined aetiology.