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. 2019 Aug 28;11(16):6569–6583. doi: 10.18632/aging.102211

Table 8. The relationship between ADAMTS7 rs11634042 variant and IS stratified by TOAST classification in combined IS patients.

	ADAMTS7 rs11634042
	Genotype			P value^a	Allele		P value^a	OR (95% CI)
	CC	CT	TT	P value^a	C	T	P value^a	OR (95% CI)
Control (n=1268)	863 (68.0)	360 (28.4)	45(3.6)		2086(82.3)	450(17.7)
Cases
LAA (n=812)	613(75.5)	183(22.5)	16(2.0)	0.0026	1409(86.8)	215(13.2)	4.4×10^-4	0.71(0.59-0.84)
SAA (n=355)	259(73.0)	89(25.0)	7(2.0)	0.17	607(85.5)	103(14.5)	0.057	0.79(0.62-0.99)
CE (n=46)	35(76.1)	10(21.7)	1(2.2)	0.64	80(87.0)	12(13.0)	0.25	0.70(0.38 - 1.29)
UE (n=66)	53(80.3)	12(18.2)	1(1.5)	0.17	118(89.4)	14(10.6)	0.057	0.55(0.31 -0.97)

LAA: Large-artery atherosclerosis; SAA: Small-artery atherosclerosis; CE: Cardioembolic; UE: Undetermined aetiology.