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Ara-c affected mouse growth and development by regulating INK4 family genes and the cell cycle-dependent CDK4/cyclin D1 complex.
(A) Body weight changes were measured during different injection periods with Ara-c or saline. (B-D) Organ weights were measured during injection of Ara-c or saline for three weeks. (E-F) The expression of CDK4 and cyclin D1 in organs during injection of Ara-c or saline for three weeks.
