Upregulated miR-140-5p suppresses synoviocytes apoptosis in synovial tissues of rats with KOA. a, results of TUNEL staining (400 ×); b, the mRNA expression of Bax and Bcl-2 was detected by RT-qPCR; c, protein bands of Bax and Bcl-2; d, the statistical results of expression of Bax and Bcl-2 in the synovial tissues in each group by Western blot analysis, * P < 0.05 vs the control group, # P < 0.05 vs the ACLT group. N = 10, * P < 0.05 vs the control group, # P < 0.05 vs the ACLT group. The measurement data conforming to the normal distribution were expressed as mean ± standard deviation. ANOVA was used for comparisons among multiple groups. Tukey’s multiple comparisons test was used for pairwise comparisons after ANOVA.