Upregulated miR-140-5p induces proliferation of synoviocytes of KOA rats. a, the results of colony formation assay; b, comparison of colony cells among each group; c, comparison of cell proliferation ability among each group, * P < 0.05 vs the control group, # P < 0.05 vs the ACLT group. The experiment was repeated for three times. The measurement data conforming to the normal distribution were expressed as mean ± standard deviation. ANOVA was used for comparisons among multiple groups. Tukey’s multiple comparisons test was used for pairwise comparisons after ANOVA.