Figure 9.

Upregulated miR-140-5p represses inflammation reaction of synoviocytes in rats with KOA. a, the expression of IL-1β and TNF-α in the serum of synoviocytes in each group was detected by ELISA; b, the expression of IL-1β and TNF-α of synoviocytes was detected by RT-qPCR; * P < 0.05 vs the normal group, # P < 0.05 vs the ACLT group. The experiment was repeated for three times. The measurement data conforming to the normal distribution were expressed as mean ± standard deviation. ANOVA was used for comparisons among multiple groups. Tukey’s multiple comparisons test was used for pairwise comparisons after ANOVA.