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HMGB1 regulates the expression levels of several osteoarthritis-related genes in chondrocytes.
(a) Interference of siRNAs for HMGB1 was confirmed by Western blot. Relative mRNA levels were evaluated at 6 h (b) and 24 h (c) respectively. Data are expressed as Mean ± SEM (n = 3). Values with p < 0.05 were considered to be statistically significant. *P < 0.05, **P < 0.01, ***P < 0.001 vs. control group; #P < 0.05, ##P < 0.01 vs. LPS group.
