TABLE II.

Ex Vivo Colony-Forming Unit (CFU) Data in Figure 5-C ^*

	Mean CFUs and SEM	P Value†
Specimen source: tissue		<0.001
—/—	1.4 × 108 ± 2.1 × 107
Lin/Lin + Rif	None detected (below LOD)
Specimen source: bone		<0.05
—/—	6.9 × 106 ± 3.1 × 106
Lin/Lin + Rif	None detected (below LOD)
Specimen source: implant		<0.05
—/—	5.1 × 105 ± 2.2 × 105
Lin/Lin + Rif	None detected (below LOD)

^*The rabbit model of orthopaedic implant-associated infection (OIAI) involved the surgical placement of coated implants without (−/−) or with (Lin/Lin + Rif) antibiotics. N = 6 rabbits per experimental group. On day 7, the rabbits were killed and tissue (muscle/tendon), bone, and implant specimens were harvested and processed to determine ex vivo CFUs (mean and standard error of the mean [SEM]). LOD = limit of detection (for tissue: 2 × 10³ CFUs; bone: 5 × 10² CFUs; implant: 2 × 10¹ CFUs).

^†Two-tailed Student t test.