Table 3. Comparison of incidence and hazard ratio of acute pancreatitis between patients with and without kidney transplantation stratified by gender, age, and comorbidity.
| Kidney transplantation | ||||||||
|---|---|---|---|---|---|---|---|---|
| No | Yes | |||||||
| Event | PY | Rate# | Event | PY | Rate# | Crude HR (95% CI) | Adjusted HR† (95% CI) | |
| Gender | ||||||||
| Women | 4 | 17863 | 0.22 | 28 | 16566 | 1.69 | 7.57(2.65, 21.6)*** | 7.71(2.68, 22.2)*** |
| Men | 11 | 18031 | 0.61 | 26 | 17873 | 1.45 | 2.42(1.19, 4.89)* | 1.97(0.95, 4.10) |
| P for interaction | 0.32 | |||||||
| Stratify age | ||||||||
| ≤ 49 | 6 | 26219 | 0.23 | 33 | 23284 | 1.42 | 6.30(2.64, 15.0)*** | 5.24(2.15, 12.8)*** |
| 50–64 | 6 | 6178 | 0.97 | 20 | 10191 | 1.96 | 1.94(0.78, 4.85) | 1.75(0.69, 4.46) |
| ≧ 65 | 3 | 3498 | 0.86 | 1 | 964 | 1.04 | 1.11(0.12, 10.7) | 1.77(0.13, 23.6) |
| P for interaction | 0.07 | |||||||
| Comorbidity‡ | ||||||||
| No | 9 | 30201 | 0.30 | 24 | 20202 | 1.19 | 4.04(1.88, 8.70)*** | 3.94(1.83, 8.48)*** |
| Yes | 6 | 5693 | 1.05 | 30 | 14238 | 2.11 | 2.01(0.83, 4.82) | 2.39(0.96, 5.96) |
| P for interaction | 0.24 | |||||||
Rate#, incidence rate, per 1,000 person-years; Crude HR, relative hazard ratio; Variables found to be statistically significant in the univariable model were further included in the multivariable model.
†Adjusted for age, alcohol-related illness, gall stone, HCV, HBV, and diabetes.
‡ Patients with any one of the comorbidities alcohol-related illness, gall stone, HCV, HBV, CMV, polycystic kidney disease, hyperlipidemia, and diabetes were classified as the comorbidity group
*p<0.05,
***p<0.001.