Table 4. Incidence rates and hazard ratios of acute pancreatitis among kidney transplantation patients stratified by treatment.
| Variables | N | Event | Person-years | Rate# | Crude HR (95% CI) | Adjusted HR† (95% CI) |
|---|---|---|---|---|---|---|
| Steroid | ||||||
| No | 5027 | 52 | 33007 | 1.58 | 1(Reference) | 1(Reference) |
| Yes | 209 | 2 | 1433 | 1.40 | 0.89(0.22, 3.64) | 0.83(0.19, 3.65) |
| Tacrolimus | ||||||
| No | 2348 | 28 | 18747 | 1.49 | 1(Reference) | 1(Reference) |
| Yes | 2888 | 26 | 15692 | 1.66 | 1.05(0.61, 1.81) | 1.01(0.41, 2.47) |
| Cyclosporin | ||||||
| No | 2691 | 25 | 14627 | 1.71 | 1(Reference) | 1(Reference) |
| Yes | 2545 | 29 | 19812 | 1.46 | 0.90(0.52, 1.56) | 0.86(0.36, 2.03) |
| Sirolimus | ||||||
| No | 4725 | 50 | 31633 | 1.58 | 1(Reference) | 1(Reference) |
| Yes | 511 | 4 | 2807 | 1.43 | 0.88(0.32, 2.46) | 0.80(0.28, 2.29) |
| Mycophenolatemofetil | ||||||
| No | 1645 | 21 | 12104 | 1.73 | 1(Reference) | 1(Reference) |
| Yes | 3591 | 33 | 22335 | 1.48 | 0.83(0.48, 1.44) | 0.71(0.39, 1.29) |
| Certican | ||||||
| No | 5233 | 54 | 34456 | 1.57 | 1(Reference) | 1(Reference) |
| Yes | 3 | 0 | 3 | 0.00 | - | - |
| Thymoglobulin | ||||||
| No | 5114 | 53 | 33856 | 1.57 | 1(Reference) | 1(Reference) |
| Yes | 122 | 1 | 583 | 1.71 | 1.05(0.15, 7.57) | 1.15(0.16, 8.39) |
Rate#, incidence rate, per 1,000 person-years; Crude HR, relative hazard ratio; Variables found to be statistically significant in the univariable model were further included in the multivariable model.
†Adjusted for alcohol-related illness, gall stone, HCV, and diabetes.