Fig. 1.

TRIF mediates IFN-γ production during K. pneumoniae airway infection. WT and TRIF mutant mice (n = 7–8 per group) were infected with about 10⁴ CFU K. pneumoniae and sacrificed at designated time points. IFN-γ levels in the lungs of the mice were determined by cytometric bead assay (a) and qRT-PCR (b). Data are expressed as box-and-whisker diagrams depicting the smallest observation, lower quartile, median, upper quartile and largest observation. * p < 0.05, ** p < 0.01, Mann-Whitney U test. ^### p < 0.001, Fisher exact test.