Table 3.

Baseline characteristics of VASST Caucasian septic shock patients by TNFAIP2 rs8126 genotype

	AA	GG/AG	p value
	(n = 330)	(n = 189)
Age, years	64 (50 – 74)	63 (53 – 72)	0.42
Male gender, %	61.9	62.4	0.23
APACHE II	26 (21 – 32)	27 (22 – 32)	0.38
Surgery, %	21.2	22.8	0.50
Pre-existing conditions, %
Chronic heart failure	7.0	10.6	0.37
Chronic pulmonary disease	17.0	18.5	0.66
Chronic liver disease	11.2	9.5	0.82
Chronic renal failure	10.9	9.5	0.27
Chronic corticosteroid use	20.3	20.6	0.86
Cardiovascular variables on day 1
Heart rate, bpm	128 (112 – 141)	125 (108 – 135)	0.094
Mean arterial pressure, mm Hg	56 (50 – 62)	55 (49 – 61)	0.53
Central venous pressure, mm Hg	14 (11 – 17)	15 (12 – 18)	0.20
Laboratory variables on day 1
White blood cell count, 103/mm3	13.7 (7.4 – 20.5)	14.1 (8.4 – 22.4)	0.36
Platelet count, 103/mm3	152 (87 – 242)	179 (96 – 272)	0.31
PaO2/FiO2, mm Hg	197 (143 – 256)	182 (136 – 246)	0.17
Creatinine, μmol/l	141 (89 – 248)	170 (93 – 262)	0.27
Lactate, mmol/l	1.7 (0.8 – 3.3)	1.9 (1.1 – 3.8)	0.25
Microbiological results, n (%)
Culture positive for Gram-negative organism	75 (22.7)	39 (20.6)	0.66
Culture positive for Gram-positive organism	101 (30.6)	58 (30.7)	1.00
Culture positive for any primary site	183 (55.5)	105 (55.6)	0.93

Values are reported as median (IQR) unless otherwise specified. APACHE II = Acute Physiology and Chronic Health Evaluation II.