Fig. 2.

gzmA and gzmB expression in NK cells from WT mice before and during K. pneumoniae pneumonia. Mice were infected with 4 × 10³ CFU K. pneumoniae intranasally and sacrificed before and at 6, 16 and 48 h after infection. Percentage and MFI of intracellular gzmA (a, b) and gzmB (c, d) in NK cells from the lungs and blood are shown. Box-and-whisker diagrams depict the smallest observation, lower quartile, median, upper quartile and largest observation (n = 5 at each time point). * p < 0.05, ** p < 0.01 (Mann-Whitney U test).