Table 3.
Days alive and free of organ dysfunction and organ support in septic shock patients of European ancestry by VPS13D rs6685273 genotype
| TT/TC | CC | p value | |
|---|---|---|---|
| (n = 101) | (n = 397) | ||
| Days alive and free of organ dysfunction | |||
| Cardiovascular | 22 (9 - 24) | 18 (0– 24) | 0.015 |
| Respiratory | 6 (o - 17) | 3 (0– 15) | 0.072 |
| Renal | 28 (13 - 28) | 21 (3– 28) | 0.0014 |
| Hematologic | 27 (14 - 28) | 25 (7– 28) | 0.14 |
| Hepatic | 27 (ll - 28) | 26 (5– 28) | 0.17 |
| Neurologic | 19 (8 - 26) | 16 (0– 25) | 0.0088 |
| Artificial organ support | |||
| Vasopressor | 22 (10 - 24) | 19 (0– 24) | 0.020 |
| Ventilator | 14 (l - 21) | 9 (0– 20) | 0.058 |
| Acute renal | |||
| replacement therapy | 28 (17 - 28) | 25 (6– 28) | 0.0006 |
Data are denoted as the median (interquartile range) and were calculated for the 28-day study period [15]. The Mann-Whitney U test was used to calculate p values.