Table 2.

Spearman rank correlation between clinical scores or complement activity and concentration of biomarkers at baseline (upon admission) in patients with NSTI

	MBL		Ficolin-1		Ficolin-2		Ficolin-3
	p	p	p	p	p	p	p	p
SAPS II	–0.10	0.252	–0.07	0.454	–0.26	0.002	–0.02	0.847
SOFA	–0.18	0.046	–0.10	0.273	–0.17	0.059	0.02	0.821
LRINEC	–0.08	0.395	0.12	0.181	0.09	0.329	0.08	0.376
CPa	0.09	0.06	0.21	0.02	0.31	<0.0001	0.45	<0.0001
LPa	0.12	0.18	0.24	0.007	0.47	<0.0001	0.59	<0.0001
APa	0.33	<0.0001	0.37	<0.0001	0.46	<0.0001	0.40	<0.0001

SAPS II = Simplified Acute Physiology Score II; SOFA = Sepsis-Related Organ Failure Assessment score; LRINEC = Laboratory Risk Indicator for Necrotizing Fasciitis score; CP = classical pathway; LP = ficolin-mediated lectin pathway; AP = alternative pathway.

^aBaseline complement pathway residual activation capacity.