Table 4.

Diagnostic accuracy of low baseline biomarker levels in predicting 28-day mortality in patients with NSTI

	MBL	Ficolin-1	Ficolin-2	Ficolin-3
Sensitivity	0.68 (0.47 – 0.85)	0.50 (0.30 – 0.70)	0.82 (0.61 – 0.94)	0.77 (0.56 – 0.91)
Specificity	0.53 (0.49 – 0.56)	0.50 (0.46 – 0.54)	0.56 (0.52 – 0.58)	0.55 (0.51 – 0.58)
PPV	0.22 (0.15 – 0.27)	0.16 (0.10 – 0.23)	0.27 (0.20 – 0.30)	0.25 (0.18 – 0.30)
NPV	0.90 (0.83 – 0.95)	0.84 (0.77 – 0.90)	0.94 (0.87 – 0.98)	0.93 (0.86 – 0.97)
Area under the ROC curve	0.59 (0.46 – 0.72)	0.52 (0.38 – 0.66)	0.75 (0.63 – 0.86)	0.67 (0.54 – 0.80)

Data are presented as fractions (95% CI). The prevalence of 28-day mortality was 16%. Low baseline level is defined by the median.