Fig. 1.

IDGF3 mutants are more sensitive to EPN infection. a Schematic diagram of the Idgf3 gene in the mutant Idgf3^L1, which was generated by imprecise excision of NP2446, a P-element located 45 bp after transcription start of Idgf3. TS = Transcription start of the Idgf3 gene. Black box represents the 8 bp duplication at the P-element insertion site, the gray boxes represent the nontranslated region and the white boxes represent the coding regions. b Idgf3 mutant larvae (w;Idgf3^L1) are sensitive to EPN infections 48 h after infection. Heterozygotes in the Idgf3 mutation (w;Idgf3^L1/+) have similar mortality to the control (w¹¹¹⁸). Differences compared to control genotype were analyzed using the Student t test. *** p < 0.001, only significant results are shown; error bars represent SEM.