Figure 1.
High expression of lncRNA CRNDE in drug-resistant liver cancer cells. (a): RT-qPCR was used to detect the mRNA expression of genes related to drug resistance in HepG2/ADM, BEL-7402/ADM and their parent cell strains; (b): Western blot analysis was used to detect the protein expression of genes related to drug resistance in HepG2/ADM, BEL-7402/ADM and their parent cell strains; (c): RT-qPCR was used to detect the expression of CRNDE in drug-resistant cell lines HepG2/ADM, BEL-7402/ADM and their parent cell strains. * P< 0.05 vs. the parent cell strains; the data are all measurement data, expressed as mean ± standard deviation, and the two groups are compared by independent sample t-test for statistical analysis, the experiment was performed three times likewise.