Figure 5.

CRNDE acts as a ceRNA to adsorb miR-33a, thus affecting HMGA2 expression. (a): Targetscan website predicts the targeting relationship between miR-33a and HMGA2; (b): Luciferase activity assay was used to verify the targeting relationship between miR-33a and HMGA2; (c): RT-qPCR was used to detect the expression of CRNDE, miR-33a and HMGA2 after cell treatment in per group; * P< 0.05; the data are all measurement data, expressed as mean ± standard deviation, and the two groups are compared by independent sample t-test for statistical analysis. The experiment was performed three times.