Figure 2.

FBP1 gene silencing promotes PCa cell proliferation. A, MTT detection for OD values of DU-145 cell line. B, MTT detection for OD values of PC-3 cell line. The PCa cell viability was measurement data, which were presented as mean ± standard deviation and analyzed by two-way analysis of variance. The multiple comparison was analyzed by post-hoc Tukey test. The experiment was repeated three times. * p < 0.05 vs. the blank group; # p < 0.05 vs. the U0126 group; & p < 0.05 vs. the PD98059 group. NC, negative control; FBP1, fructose-bisphosphatase 1; MTT, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide; PCa, prostate cancer; OD, optical density; ANOVA, analysis of variance.