FBP1 gene silencing promotes PCa cell migration. A-B, scratch images and migration rate of DU-145 cells at 0 h and 24 h based on wound healing assay. C-D, scratch images and migration rate of PC-3 cells at 0 h and 24 h according to wound healing assay. PCa cell migration rates were measurement data, which were presented as mean ± standard deviation and analyzed by one-way ANOVA. The multiple comparison was analyzed by post-hoc Tukey test. The experiment was repeated three times.* p < 0.05 vs. the blank group; # p < 0.05 vs. the U0126 group; & p < 0.05 vs. the PD98059 group. NC, negative control; FBP1, fructose-bisphosphatase 1; PCa, prostate cancer; ANOVA, analysis of variance.