Figure 7.

FBP1 gene silencing increases growth of PCa tumor. A, images of xenograft tumors in nude mice after subcutaneous inoculation of DU145 cells. B, growth curves for tumor volume in each group after subcutaneous inoculation of DU145 cells. C, relative tumor weight in each group after subcutaneous inoculation of DU145 cells. The growth results and relative weight of tumor was measurement data, which were presented as mean ± standard deviation and analyzed by one-way ANOVA. The multiple comparison was analyzed by post-hoc Tukey test. The experiment was repeated three times; the sample size for each group was 15 nude mice; *, p < 0.05 vs. the blank group; NC, negative control; FBP1, fructose-bisphosphatase 1; PCa, prostate cancer; ANOVA, analysis of variance.