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. Author manuscript; available in PMC: 2020 Sep 30.
Published in final edited form as: Arch Biochem Biophys. 2019 Aug 22;673:108078. doi: 10.1016/j.abb.2019.108078

Table 7.

Genetic regulatory mechanisms: CYP3A4 vs. CYP3A7.

Nuclear Receptor/Transcription Factor NRNC Abbreviation: Nuclear Receptor/Transcription Factor Full Name: CYP3A4 CYP3A7
PXR Pregnane X receptor Yes Yes
CAR Constitutive Androstane receptor Yes No
FXR Farnesoid X receptor Yes No
Sp1 Specificity protein 1 ? Yes
Sp3 Specificity protein 3 ? Yes
USF1 Upstream stimulatory factor 1 ? Yes
NF1 Nuclear factor 1 Yes Yes
HNF-3β Hepatocyte nuclear factor 3β Yes Yes
HNF-4α Hepatocyte nuclear factor 4α Yes Yes
GR Glucocorticoid receptor No Yes
C/EBP CCAAT enhancer binding protein Yes Yes
NFkB Nuclear factor kappa light chain enhancer of activated B cells Yes Yes
XREM Xenobiotic response enhancer module Yes Yes
DBP D-element binding protein Yes No