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. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Hypertension. 2019 Aug 19;74(4):817–825. doi: 10.1161/HYPERTENSIONAHA.119.13382

Figure 1 – Validation of smooth muscle-specific Bbs1 knockout mice.

Figure 1 –

(A) Representative confocal images of aortic rings from tamoxifen (Tx)-treated SMCreERT2/Bbs1F/F and wildtype mice visualized for td-Tomato (red) and von Willebrand factor (green) at low (top) and high (bottom) magnification. (B) Bbs1 mRNA expression of aortic rings from tamoxifen-treated SMCreERT2/Bbs1F/F and wildtype mice (n=6/group; *p<0.05 via unpaired t-test). (C) Total body weight and (D) weight gain after tamoxifen treatment in SMCreERT2/Bbs1F/F and wildtype mice (n=8/group), bar: 100μm.