Skip to main content
. Author manuscript; available in PMC: 2020 Oct 1.
Published in final edited form as: Cell Immunol. 2019 Jul 3;344:103949. doi: 10.1016/j.cellimm.2019.103949

Figure 7. PAR4 deficiency is associated with increased lung injury and mortality after IAV infection.

Figure 7.

Wild-type (WT, white circles) and PAR4−/− (ΔPAR4, black circles) mice were infected with H1N1 IAV. A) Lung injury was quantified by total protein concentration in BALF prior, 5 and 7 days after infection. Changes in body weights (B) and calculated survival (C) over 14 days after infection (N=17 for WT and N=23 for ΔPAR4). Body weights before infection were set to 100%. Data (mean ± SEM) and calculated survival were analyzed by 2‐way ANOVA (A and B) or log‐rank test (C). *P<0.05