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. Author manuscript; available in PMC: 2020 Nov 1.
Published in final edited form as: Cytokine. 2019 Jun 18;123:154759. doi: 10.1016/j.cyto.2019.154759

Figure 1: Plasma levels of inflammatory mediators distinguish PTB from EPTB in Chinese patients.

Figure 1:

(A-B) Plasma levels of cytokines, soluble receptors and eicosanoids were assessed in samples from patients with pulmonary TB (n=94) or extrapulmonary TB (n=50). Data were log10 transformed and z-score normalized. (A) A hierarchical cluster analysis (Ward’s method with 100X bootstrap) was employed to test whether the overall expression profile of the biomarkers could separate the study groups. Dendrograms represent Euclidean distance. (C) Discrimination of groups using combination of plasma biomarkers. In an exploratory approach, a sparse canonical correlation analysis (sCCA) was employed to test whether patient groups could be distinguished. (D) Canonical discriminant was performed to evaluate the biomarkers responsible for the difference between groups in model.