Table 1.
Baseline characteristics by randomization assignment and by atenolol status, Mean (SD) or %
| Chlorthalidone | Amlodipine | Lisinopril | No Atenolol | Atenolol | |
|---|---|---|---|---|---|
| Characteristic | N=11,000* | N=6,522* | N=6,442* | N=23,036 | N=928 |
| Age, years | 69.8 (6.8) | 69.8 (6.8) | 69.9 (6.8) | 69.9 (6.8) | 69.1 (6.3) |
| Age ≥ 75 years, % | 23.2 | 23.8 | 24.2 | 23.8 | 19.9 |
| Women, % | 45.1 | 45.5 | 44.2 | 45.2 | 39.9 |
| Race and Ethnicity, % | |||||
| White, non-Hispanic | 49.5 | 50.3 | 49.5 | 48.8 | 71.2 |
| Black, non-Hispanic | 31.1 | 31.3 | 31.0 | 31.8 | 15.0 |
| White Hispanic | 12.0 | 11.5 | 12.3 | 12.1 | 8.0 |
| Black Hispanic | 3.1 | 3.0 | 3.2 | 3.1 | 1.7 |
| Other | 4.4 | 4.0 | 4.1 | 4.2 | 4.1 |
| Systolic blood pressure, mm Hg | 146.6 (15.7) | 146.5 (15.6) | 146.8 (15.6) | 146.5 (15.6) | 149.2 (16.2) |
| Diastolic blood pressure, mm Hg | 83.1 (10.1) | 82.9 (10.1) | 83.0 (10.0) | 83.0 (10.1) | 83.4 (10.3) |
| Body mass index, kg/m2 | 29.3 (6.0) | 29.3 (5.9) | 29.3 (5.9) | 29.3 (6.0) | 29.0 (5.6) |
| Obesity, % | 38.9 | 39.0 | 38.8 | 39.0 | 37.7 |
| Type 2 diabetes status, % | 42.6 | 43.0 | 42.2 | 42.9 | 35.5 |
| Prior cardiovascular disease, % | 56.1 | 54.6 | 55.7 | 54.8 | 75.5 |
| Smoking Status, % | |||||
| Never | 38.4 | 38.6 | 38.5 | 38.6 | 35.6 |
| Former | 43.1 | 42.5 | 43.2 | 42.7 | 49.5 |
| Current | 18.5 | 18.9 | 18.2 | 18.7 | 15.0 |
*
Reduced denominators (c/a/l) for smoking=11,000/6,521/6,441; BMI/obesity=10,964/6,494/6,422; diabetes=10,222/6,057/5,986