Table 1.
Distribution of MLSTs among AMP-S and AMP-R E. coli, and identification of ß-lactamase genes in ß-lactam-resistant isolates.
| No. (%) of isolates that are: | |||||
|---|---|---|---|---|---|
| MLST (complex) | No. (%) of isolates | AMP-Sb | AMP-R | P valuec | bla genes in AMP-R isolates (no. of isolates)d |
| ST95 (ST95 cplx) | 56 (20.5) | 34(18.1) | 22 (25.9) | 0.140 | blaTEM (22) |
| ST69 (ST69 cplx) | 31 (11) | 14 (7.4) | 17 (20.0) | 0.003 | blaTEM (17), blaOXA (1) |
| ST420 | 31 (11) | 31 (16.5) | 0 | <0.0001 | |
| ST73 (ST73 cplx) | 27 (10) | 15 (8.0) | 12 (14.1) | 0.116 | blaTEM (11), blaSHV (1) |
| ST127 | 21 (8) | 19 (10.1) | 2 (2.4) | 0.027 | blaTEM (2) |
| ST404 (ST14 cplx) | 9 (3) | 1 (0.5) | 8 (9.4) | 0.0005 | blaTEM (8) |
| ST10 (ST10 cplx) | 8 (3) | 5 (2.7) | 3 (3.5) | 0.707 | blaTEM (3) |
| ST12 (ST12 cplx) | 8 (3) | 5 (2.7) | 3 (3.5) | 0.707 | blaTEM (1), blaSHV (2) |
| ST62 | 6 (2) | 5 (2.7) | 1 (1.2) | 0.669 | blaTEM (1) |
| ST141 | 5 (2) | 5 (2.7) | 0 | 0 329 | |
| ST131 (ST131 cplx) | 4 (1.5) | 2 (1.1) | 2 (2.4) | 0 591 | blaTEM (2) |
| ST144 | 4 (1.5) | 3 (1.6) | 1 (1.2) | 1.0 | blaTEM (1) |
| ST405 (ST405 cplx) | 4 (1.5) | 1 (0.5) | 3 (3 5) | 0 001 | blaTEM (3) |
| ST14 (ST14 cplx) | 3 (1) | 2 (1.1) | 1 (12) | 1 0 | blaTEM (1) |
| ST372 | 3 (1) | 3 (1.6) | 0 | 0 555 | |
| ST555 (ST538 cplx) | 3 (1) | 2 (1.1) | 1 (12) | 1.0 | blaTEM (1) |
| ST58 (ST155 cplx) | 2 (0.8) | 1 (0.5) | 1 (12) | 0 527 | blaTEM (1) |
| ST88 (ST23 cplx) | 2 (0.8) | 1 (0.5) | 1 (12) | 0 527 | blaTEM (1) |
| ST106 (ST69 cplx) | 2 (0.8) | 2 (1.1) | 0 | 1.0 | |
| ST297 | 2 (0.8) | 2 (1.1) | 0 | 1.0 | |
| ST393 (ST31 cplx) | 2 (0.8) | 1 (0.5) | 1 (1.2) | 0.527 | blaTEM (1) |
| ST410 (ST23 cplx) | 2 (0.8) | 2 (1.1) | 0 | 1.0 | |
| ST491 | 2 (0.8) | 2 (1.1) | 0 | 1.0 | |
| ST706 | 2 (0.8) | 2 (1.1) | 0 | 1.0 | |
| ST998 | 2 (08) | 1 (0.5) | 1 (1.2) | 0.527 | blaTEM (1), blaCTX-M (1) |
| ST38 (ST38 cplx) | 1 (04) | 0 | 1 (1.2) | 0.311 | blaOXA (1) |
| ST394 (ST394 cplx) | 1 (04) | 0 | 1 (1.2) | 0.311 | blaOXA (1) |
| ST1604 | 1 (04) | 0 | 1 (1.2) | 0.311 | blaTEM (1) |
| ST2328 | 1 (04) | 0 | 1 (1.2) | 0.311 | blaTEM (1) |
| ST2617 | 1 (04) | 0 | 1 (1.2) | 0.311 | blaTEM (1) |
| Other STsa | 27 (10) | 27 (14.4) | 0 | ||
| Total (% of total) | 273 (100) | 188 (69) | 85 (31) | blaTEM (81; 95%), blaSHV (3; 4%), blaOXA (2; 2%), blaCTX-M (1; 1%) | |
AMP-S, susceptible to ampicillin/all ß-lactams tested; AMP-R, resistant to at least ampicillin.
Includes ST59, ST80, ST93, ST101, ST126, ST136, ST155, ST348, ST357, ST550, ST641, ST847, ST906, ST963, ST1147, ST1155, ST1633, ST1859, ST1946, ST2178, ST2227, ST2562, ST2567, ST4044, ST6092, and two unknown STs.
157 (84%) of 188 AMP-S isolates were susceptible to other tested agents.
The P value compares the AMP-S column and AMP-R column. Bolded values are statistically significant.
Sequences identified include blaOXA-1, blaSHV-1, and blaCTX-9/51, and of the 36 blaTEM sequences typed, 8% were blaTEM-1A, 69% were blaTEM-1B, and 22% were blaTEM-1C.