Skip to main content
. 2019 Sep 10;10(52):5480–5491. doi: 10.18632/oncotarget.27190

Figure 4. Up-regulation of CD24 correlates with CXCR4 and CD38 expression in MM cells.

Figure 4

(A) Representative dot plots of CD24 and CXCR4 expression before and after incubation with BMSCs. (B) Fold increase in expression of CXCR4, CD24 and double positive CXCR4/CD24 cells after 5 days incubation of MM cells with BMSC of patients with MM. Fold increase was significant (p < 0.0011–0.0002, n = 8). (C) Fold increase in expression of CD38, double positive CD38/CXCR4 and CD38/CD24 cells after 5 days incubation of MM cells with BMSC of patients with MM. Fold increase was significant (P < 0.03–0.0013, n = 8). (D) Mean fluorescence intensity (MFI) of CXCR4 expression on CD24 positive (+) and CD24 negative (-) plasma cells of multiple myeloma patients. (P < 0.03, n = 10). (E) Changes in expression of other markers were assessed. No significant upregulation was detected (n = 5)