Table 1. Multivariat analysis including established prognostic parameters and the “PSA pattern score” (PSA score).
Tumor subset | Scenario | p -value | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
n analyzable | preoperative PSA-Level | pT Stage | cT Stage | Gleason grade prostatectomy | Gleason grade biopsy | pN Stage | R Stage | PSA score | ||
all cancers | 1 | 6,923 | <0.0001 | <0.0001 | — | <0.0001 | — | <0.0001 | <0.0001 | <0.0001 |
2 | 10,552 | <0.0001 | <0.0001 | — | <0.0001 | — | — | <0.0001 | <0.0001 | |
3 | 10,392 | <0.0001 | — | <0.0001 | <0.0001 | — | — | — | <0.0001 | |
4 | 8,878 | <0.0001 | — | <0.0001 | — | <0.0001 | — | — | <0.0001 | |
ERG-negative cancers | 1 | 2,723 | 0.0002 | <0.0001 | — | <0.0001 | — | 0.0008 | 0.0848 | <0.0001 |
2 | 4,245 | <0.0001 | <0.0001 | — | <0.0001 | — | — | 0.0033 | <0.0001 | |
3 | 4,206 | <0.0001 | — | <0.0001 | <0.0001 | — | — | — | <0.0001 | |
4 | 4,138 | <0.0001 | — | <0.0001 | — | <0.0001 | — | — | <0.0001 | |
ERG-positive cancers | 1 | 2,134 | 0.0225 | <0.0001 | — | <0.0001 | — | 0.2417 | 0.0002 | 0.0226 |
2 | 3,339 | 0.0002 | <0.0001 | — | <0.0001 | — | — | <0.0001 | 0.0295 | |
3 | 3,282 | <0.0001 | — | <0.0001 | <0.0001 | — | — | — | 0.0042 | |
4 | 3,229 | <0.0001 | — | <0.0001 | — | <0.0001 | — | — | <0.0001 |
For definition of the scenarios, see Statistics section.