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. Author manuscript; available in PMC: 2020 Mar 15.
Published in final edited form as: J Immunol. 2019 Aug 19;203(6):1609–1618. doi: 10.4049/jimmunol.1801648

Figure 1. Influenza vaccination enhances IL-15 stimulated cytokine production.

Figure 1

Baseline (white bars) and 30 day post-vaccination (grey bars) PBMC samples were cultured with medium (n=10), 0.75ng/ml IL-15 alone (n=26), inactivated H3N2 (n=10) or H3N2 + IL-15 (n=26) for 18 hours and culture supernatants were collected. Concentrations (pg/ml) of GM-CSF (a), IL-10 (b), IL-1β (c), IFN-α2 (d), IL-12(p70) (e), TNFα (f), and IFN-γ (g) in supernatant were determined by Luminex. Graphs show one dot per donor, with a bar representing median value. Comparisons between vaccination time points were made using Wilcoxon signed-rank test. *p < 0.05, **p < 0.01, *** p < 0.001.