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. Author manuscript; available in PMC: 2019 Oct 16.
Published in final edited form as: Ann Intern Med. 2019 Mar 26;170(8):538–546. doi: 10.7326/M18-3542

Figure 5.

Figure 5

Forest plot for headaches example, showing results of the threshold analysis applied to the combined evidence on each comparison and the GRADE quality ratings. The base-case optimal set of treatments is 3, 6, 7 (amitriptyline, topiramate, propranolol).

NT – no threshold: no amount of change in this direction would change the recommendation. At either side of the invariant interval are shown the new set of optimal treatments if threshold exceeded in this direction.