Forest plot for headaches example, showing results of the threshold analysis
applied to the combined evidence on each comparison and the GRADE quality
ratings. The base-case optimal set of treatments is 3, 6, 7 (amitriptyline,
topiramate, propranolol).
NT – no threshold: no amount of change in this direction would change the
recommendation. At either side of the invariant interval are shown the new set
of optimal treatments if threshold exceeded in this direction.