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a–d Adjuvant chemotherapy use in patients who received the 70-gene signature versus patients who did not receive the 70-gene signature in different guideline delineated subgroups: group A (BR I, > 2 cm, N0) (n = 218); group B (BR II, > 1 cm, N0) (n = 3571); group C (BR I/II, any size, Nmi) (n = 1040); and group D (BR I/II, any size, N1a) (n = 1888). P values were calculated using a χ2 test for differences in categorical data
