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. 2019 Sep 11;10(9):670. doi: 10.1038/s41419-019-1873-x

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a–d Heatmap representing the log2 (abundances) of the differentially expressed genes in the selected KEGG pathways in miR-133a overexpressed HFL cells as compared to the CTL groups. The color key from blue to red represents the log2 (abundances) from low to high. e The overlap between Targetscan predicted miR-133a targets and miR-133a-down-regulated proteins identified by quantitative proteomics. f 22 overlapping proteins were analyzed and shown as Heatmap clusters