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. 2019 Sep 11;9:13084. doi: 10.1038/s41598-019-49234-6

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Pathway enrichment analysis of 95 cSABPs using the Reactome database (https://reactome.org/). (A) Biological pathways associated with the 95 cSABPs are highlighted by dark to bright red colors based on their enrichment levels (logFC) compared to their basal levels in the HEK 293 cells¹⁸. Note that a few reactome pathways, including digestion and ingestion (DA), circadian clock (Cir), DNA repair (Drp), DNA replication (DR) and reproduction (R), were not associated with any cSABPs. (B) Number of cSABPs found to be functional in different pathways. Explanation of pathway abbreviations is provided on the right.