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. 2019 Sep 11;9:13084. doi: 10.1038/s41598-019-49234-6

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Association of cSABPs with human disorders/diseases. (A) Human cSABP-disorder/disease network (SDN). In SDN, each node corresponds to a distinct cSABP (orange-colored circle with black outline) or human disorder/disease (which are color-coded). The cSABP node size is proportional to the enrichment level (Log FC) of the cSABP over that in the quantitative proteome database of HEK293 cells. The different disorders/diseases were grouped into 22 primary disorder/disease classes and color coded as shown on the right. cSABP nodes are linked to disorder/disease nodes by gray lines. For a complete set of names, see Supplementary Table S5. (B) The number of disorders/diseases associated with the 20 most implicated cSABPs. (C) A pie chart showing the relative number of disorders/diseases related to the 95 cSABPs.