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. 2019 Sep 11;10:4109. doi: 10.1038/s41467-019-11893-4

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — CD56 enhanced anti-apoptosis capability of CAR-T cells. a Left panel, the representative flow plots of apoptotic cell proportion in Her2-CAR-T, PTL-Her2-CAR-T, and CD56-Her2-CAR-T cells after culture for 6 days with cytokine deprivation. Right panel, the percentage of Annexin V⁻ and PI⁻ cells gated as in left panel. b Left panel, the representative flow plots of apoptotic cell proportion induced by TNF-α and FasL (10 ng ml⁻¹) in various CAR-T cells. Right panel, the percentage of Annexin V⁻ and PI⁻ cells gated as in the left panel. **P < 0.01, ****P < 0.0001 (two-tailed Student’s t-test). All presented data summarizes mean ± SEM. Data shown are representative data from three independent experiments. The source data underlying a, b are provided as a Source Data file