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. 2019 Sep 11;9:13177. doi: 10.1038/s41598-019-49123-y

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Association between laboratory aspirin resistance and clinical outcomes. Symbols and conventions are the same as in Fig. 2. This meta-analysis shows significant overall increase in the incidences of death and TVR of patients with AR over those without AR, while no significant change in the incidences of MI or stroke. The overall ORs in death, MI, stroke and TVR are 2.42 (P < 0.00001), 0.95 (P = 0.79), 1.64 (P = 0.46) and 2.2 (P = 0.01) respectively. Note that the p-values mentioned here are the p-values for Z test. CI, confidence interval; ASA, aspirin; MI, myocardial infarction; TVR, target vessel revascularization.