Skip to main content
. 2019 Sep 11;10(9):672. doi: 10.1038/s41419-019-1884-7

Fig. 2. SREBP-1 regulates the glycolytic activity of HCC cells.

Fig. 2

a Extracellular acidification rate (ECAR) measurement in high metastatic MHCC97-H cells transfected with control or SREBP-1 siRNAs. b ECAR measurement in low metastatic MHCC97-L cells transfected with empty or SREBP-1-expressing vectors. c Oxygen-consumption rate (OCR) measurement in MHCC97-H cells from a. d OCR measurement in MHCC97-L cells from c. e MHCC97-H cells were treated with the indicated concentrations of Betulin (100, 30, 10, 3, 1, 0.3, or 0.1 μmol/L). Next, the cells were harvested for quantitative RT-PCR. The inhibition rates of Betulin on gene expression were calculated and shown by a heatmap