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. 2019 Sep 11;10:4129. doi: 10.1038/s41467-019-12027-6

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© The Author(s) 2019

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — AI-1 regulates cell growth rate in co-cultures. a PH04 pAHL-HPr (abbreviated as HPr) co-cultured with PH04 pCT6 (abbreviated PH04). Each culture was inoculated 0.5% for an initial HPr fraction of ~0.5. Indicated AI-1 level was added during inoculation. Samples were collected for analysis of co-culture composition after 8 h. Error bars represent s.d. of technical quadruplicates. b PH04 pAHL-HPr (abbreviated as HPr) co-cultured with TOP10 pT5G (abbreviated as TOP10). Each culture was inoculated 0.5% for an initial HPr fraction of ~0.5. Indicated AI-1 level was added during inoculation. Samples were collected for analysis of co-culture composition after 8 h. Error bars represent s.d. of technical triplicates. c PH04 pAHL-HPr (abbreviated as HPr) co-cultured with PH04 pSox-LasI with or without 1 µM PYO induction. Initial fraction HPr in co-culture was ~0.5. Samples collected for AI-1 measurement after 2 h and 4 h and co-culture composition analysis after 5 h. Error bars represent s.d. of biological duplicates. Source data are provided as a Source Data file