Table 3.

Functions identified in the transcriptome and proteome of strain LA-SOL3 relevant for pathogenicity.

	Function	Contribution to pathogenicity	Reference
Siderophores	Iron-chelating ligands. Iron transport compounds.	Intracellular iron storage compounds. Suppress the growth of other microorganisms.	Renshaw et al.50
Toxins	Polyketides that include a range of compounds as mycotoxins and spore pigments.	Toxic to plants and/or animals. Mode of action extremely variable, depending on the produced compound.	Gaffoor et al.51 Chauhan et al.52
Allergens	Sensitization with extraneous allergens. Fugal allergens are usually proteins, polysaccharides, or glycoproteins.	IgE-mediated hypersensitivity in humans. The major allergic manifestations are asthma, rhinitis, allergic bronchopulmonary mycoses, hypersensitivity pneumonitis.	Fukutomi & Taniguchi53
MAPKs	Mitogen-activated protein kinases that function as key signal transduction components.	Fungal MAPKs help to promote the penetration of host tissues governing appressorium formation and virulence.	Hamel et al.18 He et al.23
HSPs	Involved in several common biological activities, such as transcription, translation, protein folding, and aggregation and disaggregation of proteins.	Involved in stress response. Different families of HSP are expressed depending on stress type, e.g.: pH, heat, cold or osmotic stress.	Tiwari et al.21
Nudix effectors	Maintenance of proper cellular processes and physiological homeostasis by sensing and modulation levels of their substrates like nucleotide sugars, deoxyribonucleoside triphosphate and capped mRNAs.	Manipulation of host defence systems.	Dong & Wang54
Velvet complex	Regulation of fungal development and secondary metabolism.	Promotion of chromatin accessibility and expression of biosynthetic gene clusters involved pathogenicity as mycotoxins, pigments and hormones.	López-Berges et al.55 Niehaus et al.26