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. 2019 Sep 11;7(17):e14220. doi: 10.14814/phy2.14220

Figure 3.

Figure 3

Summary of results showing that 24‐h TNFα (100 ng/mL) exposure increased maximum specific force (F max) evoked by ACh stimulation (A). Exposure to TNFα (100 ng/mL for 24 h) increased sensitivity to ACh as reflected by a decrease in the ACh concentration that induced 50% F max (EC50) (B). Values are medians – IQR *Significant difference (P < 0.05) from control (n = 6 animals). TNFα, tumor necrosis factor alpha; ACh, acetylcholine; IQR, interquartile range.