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. 2019 Sep 10;80(4):462–471. doi: 10.15288/jsad.2019.80.462

Table 3.

Effects of family substance use disorders on proband risk: Path analysis model results

graphic file with name jsad.2019.80.462tbl3.jpg

Path Complete sample
 Restricted sample
OR [95% CI]
 p OR [95% CI]
 p
Trimmed path model result
 Family AUD → proband AUD 1.49 [1.24, 1.78] <.001 1.47 [1.21, 1.79] <.001
 Family CUD → proband CUD 1.70 [1.32, 2.20] <.001 1.73 [1.28, 2.32] <.001
 Family AMP → proband AMP 2.33 [1.51, 3.59] <.001 2.70 [1.66, 4.40] <.001
 Family HUD → proband HUD 3.38 [1.72, 6.67] <.001 3.06 [1.32, 7.11] .009
Full path model results
 Family AUD → proband AUD 1.45 [1.19, 1.75] <.001 1.46 [1.18, 1.81] .001
 Family CUD → proband AUD 1.18 [0.89, 1.55] .245 1.21 [0.89, 1.65] .232
 Family AMP → proband AUD 0.94 [0.63, 1.41] .776 0.84 [0.54, 1.30] .425
 Family HUD → proband AUD 0.94 [0.55, 1.60] .820 0.88 [0.49, 1.60] .682
 Family AUD → proband CUD 1.18 [0.95, 1.47] .138 1.44 [1.12, 1.85] .004
 Family CUD → proband CUD 1.47 [1.08, 1.99] .013 1.42 [1.00, 2.03] .052
 Family AMP → proband CUD 0.97 [0.64, 1.48] .897 0.95 [0.59, 1.52] .832
 Family HUD → proband CUD 1.69 [0.97, 2.92] .062 1.44 [0.76, 2.72] .258
 Family AUD → proband AMP 1.36 [1.02, 1.83] .037 1.65 [1.17, 2.34] .005
 Family CUD → proband AMP 1.01 [0.66, 1.54] .975 0.88 [0.54, 1.43] .600
 Family AMP → proband AMP 1.62 [0.97, 2.70] .064 1.84 [1.03, 3.27] .038
 Family HUD → proband AMP 2.20 [1.13, 4.29] .020 2.20 [0.95, 5.10] .065
 Family AUD → proband HUD 1.55 [1.04, 2.32] .033 1.65 [1.01, 2.70] .045
 Family CUD → proband HUD 0.96 [0.49, 1.86] .899 1.04 [0.44, 2.41] .935
 Family AMP → proband HUD 0.76 [0.31, 1.83] .534 0.92 [0.33, 2.53] .866
 Family HUD → proband HUD 3.34 [1.32, 8.42]
 .011
 2.58 [0.81, 8.20]
 .108
Model comparison test χ2 difference
 df
 p
 χ2 difference
 df
 p
Trimmed vs. full model 21.40 12 .045 24.50 12 .017

Notes: Statistically significant effects (p < .05) are bolded. OR = odds ratio; CI = confidence interval; AUD = alcohol use disorder; CUD = cannabis use disorder; AMP = amphetamine use disorder; HUD = hallucinogen use disorder. See Table 1 for notes on the definitions of the complete and restricted samples.