Skip to main content
. 2019 Sep 11;2(9):e1911130. doi: 10.1001/jamanetworkopen.2019.11130

Figure 2. Associations Between PCSK9 Cohorts and Sepsis Outcomes.

Figure 2.

Outcomes include sepsis, cardiovascular failure, and in-hospital death. A, Associations between PCSK9 functional gene variants and outcomes are adjusted for age, sex, and comorbidities. B and C, Associations between the PCSK9 genetic risk score (GRS) and estimated PCSK9 expression and outcomes are stratified by tertiles and adjusted for age, sex, and comorbidities. EET indicates estimated expression tertile; LOF loss-of-function variant; OR, odds ratio.

aIndicates a gain-of-function variant.