Table 2.
Risk factors for underuse of anticoagulants in patients with moderate-to-high risk NVAF and patients with VAF.
| Risk factors | NVAF | VAF | ||||
|---|---|---|---|---|---|---|
| OR | 95% CI | p-Value | OR | 95% CI | p-Value | |
| Age (per 10 years) | 1.122 | (1.040, 1.210) | 0.003 | 1.517 | (1.277, 1.802) | <0.001 |
| SBP (per 10 mmHg) | 1.102 | (1.051, 1.155) | <0.001 | 0.855 | (0.744, 0.982) | 0.026 |
| DBP (per 10 mmHg) | 1.356 | (1.106, 1.662) | 0.003 | |||
| Regions (vs middle) | ||||||
| Northeast | 1.900 | 1.164, 3.101 | 0.010 | |||
| East | 1.438 | 1.176, 1.760 | <0.001 | |||
| West | 1.270 | 0.969, 1.665 | 0.083 | |||
| Hospital level (vs tertiary) | 0.420 | 0.324, 0.543 | <0.001 | 0.539 | (0.335, 0.865) | 0.010 |
| Type of AF (vs persistent/permanent) | ||||||
| New-onset | 1.857 | 1.412, 2.441 | <0.001 | 1.978 | (0.975, 4.013) | 0.059 |
| Paroxysmal | 1.768 | 1.470, 2.128 | <0.001 | 1.761 | (1.072, 2.895) | 0.026 |
| Dyslipidemia | 0.718 | 0.591, 0.873 | 0.001 | |||
| History of CAD | 0.198 | (0.061, 0.644) | 0.007 | |||
| History of thromboembolism | 0.640 | 0.520, 0.789 | <0.001 | |||
| Antiarrhythmic treatment | 0.359 | 0.271, 0.475 | <0.001 | 0.461 | (0.258, 0.823) | 0.009 |
AF: atrial fibrillation; CAD: coronary artery disease; CI: confidence interval; DBP: diastolic blood pressure; NVAF: non-valvular atrial fibrillation; OR: odds ratio; SBP: systolic blood pressure; VAF: valvular atrial fibrillation.