Table 2.
1997-2001 | 2009-2011 | p∗ | |
---|---|---|---|
Endothelial-Independent Coronary Reactivity (CFR-Ado) | n=162 | n=222 | |
Mean CFR-Ado | 2.6 ± 0.8 | 2.7 ± 0.6 | 0.35 |
Median (IQR) | 2.5 (2.1, 3.0) | 2.6 (2.2, 2.9) | 0.26 |
% with CFR < 2.5 | 48 | 40 | 0.12 |
% with CFR <2.32 | 36 | 31 | 0.27 |
| |||
Endothelial-Dependent Reactivity (Δ Diam to ACH) | n=107 | n=162 | |
Mean Δ Diam | 1.6 ± 12.8 | 0.2 ± 10.0 | 0.34 |
Median (IQR) | 2.6 (-6.4, +10.0) | -0.6 (-6.4, +6.5) | 0.14 |
% with Δ Diam ≤ 0% (abnormal) | 44 | 54 | 0.10 |
| |||
Endothelial-Independent Reactivity (Δ Diam to NTG) | n=113 | n=170 | |
Mean Δ Diam | 9.8 ± 13.5 | 9.7 ± 13.0 | 0.94 |
Median (IQR) | 8.3 (2.8, 17.1) | 7.6 (1.3, 18.8) | 0.87 |
% with Δ Diam ≤ 20% (abnormal) | 83 | 78 | 0.28 |
∗ p-values by t-test, Kruskal-Wallis test, and Chi Square, where appropriate.
CFR-Ado = coronary flow reserve in response to adenosine; IQR=inter-quartile range; ACH = acetylcholine; NTG = nitroglycerin.