Figure 9.

Homo‐hexameric model of InvCΔ79 apo‐form. (a) Top view of the InvCΔ79 subunits in blue tones showing the α10‐α11 loop (red), α7‐β9 loop (yellow), and hydrophobic patch (pale green). In the inlet, reported amino acids essential for chaperone–effector interaction (L376), stalk protein interaction in EscN (E384 in InvC), and type III secretion (Y385) are shown. (b) Angled view showing in the inlet the interface of two subunits with the P‐Loop (orange), the reported amino acid for ATP co‐stabilization in orthologues (R349), and the amino acids participating in intersubunit interactions (R189 and R191). The model was built by superposing the InvCΔ79 apo‐form to the E. coli EscN homo‐hexameric cylinder (PDB ID: 6NJP) using Pymol