Figure 2.

Conformational states of MetQ. (a) The structure of Neisseria meningitides MetQ in the substrate‐free (N238A) form depicted in a ribbons representation. (b) Superposition of one domain of the l‐methionine‐bound (tv_yellow) and N238A substrate‐free (slate) forms of MetQ, revealing a hinge‐type rotation axis (green axis, approximately parallel to the viewing direction) interconverting the two conformations. (c) The hinge movement is distinct from the twist‐type rotation axis (green axis, in the plane of view) interconverting the substrate‐bound form of MetQ and the substrate‐free conformation observed in the MetNIQ complex7