Table 1.
Logistic regression analysis with adherence (> 4 h /day, 70% of the days) as the dependent variable
| Whole population | Non adherent N = 100 |
Adherent N = 550 |
Crude OR [95% CI] | p-value | Adjusted OR [95% CI] | p-value | |
|---|---|---|---|---|---|---|---|
| Demographics | |||||||
| Age (yrs) | 68 [61; 74] | 68 [60; 75] | 68 [61; 74] | 1.00 [0.98; 1.02] | 0.80 | ||
| Gender, female (%) | 173/650 (26.6) | 32/100 (32.0) | 141/550 (25.6) | 0.73 [0.46; 1.16] | 0.19 | ||
| BMI (kg/m2) | 30.8 [27.7; 34.5] | 29.4 [26.5; 32.3] | 31.1 [27.8; 34.9] | 1.07 [1.02; 1.12] | 0.003 | 1.07 [1.01; 1.13] | 0.03 |
| Initial AHI (event/h) | 39 [31; 55] | 37.9 [30.0; 52.0] | 39.0 [31.0; 57.0] | 1.01 [0.99; 1.02] | 0.16 | ||
| Active smokers (%) | 77/637 (12.1] | 13/99 (13.1) | 64/538 (11.9) | 0.89 [0.47; 1.69] | 0.73 | ||
| Beard (%) | 75/456 (16.5) | 10/64 (15.6) | 65/392 (16.6) | 1.05 [0.50; 2.18] | 0.70 | ||
| Mustache (%) | 42/456 (9.2) | 7/64 (10.9) | 35/392 (8.9) | 0.81 [0.34; 1.92] | 0.60 | ||
| No mustache no beard (%) | 339/456 (74.3) | 47/64 (73.4) | 292/392 (74.5) | Ref | 0.88 | ||
| Presence of partner | 457/640 (71.4) | 61/96 (63.5) | 396/544 (72.8) | 1.54 [0.97; 2.42] | 0.07 | 2.03 [1.18; 3.50] | 0.011 |
| Active workers | 130/632 (20.6) | 20/95 (21.1) | 110/537 (20.5) | 0.97 [0.57; 1.65] | 0.90 | ||
| ESS (VAS score) | 5 [3; 8] | 6 [3; 8] | 5 [3; 9] | 0.99 [0.95; 1.05] | 0.87 | ||
| EQ-5D-3 L | |||||||
| Problems with mobility (%) | 157/623 (25.2) | 25/94 (26.6) | 132/529 (26.6) | 0.92 [0.58; 1.51] | 0.74 | ||
| Problems with self-care (%) | 38/617 (6.2) | 6/94 (6.38) | 32/523 (6.12) | 0.96 [0.39; 2.35] | 0.92 | ||
| Problems with usual activities (%) | 124/620 (20.0) | 20/96 (20.8) | 104/524 (19.9) | 0.94 [0.55; 1.61] | 0.82 | ||
| Problems of pain/discomfort (%) | 347/623 (55.7) | 54/96 (56.3) | 293/527 (55.6) | 0.97 [0.63; 1.51] | 0.91 | ||
| Problems of anxiety/depression (%) | 240/624 (38.5) | 41/96 (42.7) | 199/528 (37.9) | 0.81 [0.52; 1.26] | 0.35 | ||
| EQ-5D-3 L Health (VAS score) | 69.8 [50.2; 80.1] | 69.2 [49.4; 80.0] | 69.9 [50.4; 80.2] | 1.01 [0.99; 1.02] | 0.17 | ||
| Device | |||||||
| Treatment duration (yrs) | 4.9 [2.1; 9.8] | 3.8 [1.3; 8.1] | 5.1 [2.3; 10.2] | 1.06 [1.01; 1.11] | 0.02 | ||
| Fixed pressure (%) | 91/650 (14.0) | 12/100 (12.0) | 79/550 (14.4) | 1.23 [0.64; 2.35] | 0.53 | ||
| 90th/95th Pressure (cmH2O) | 10.0 [8.30; 11.8] | 9.9 [8.0; 11.5] | 10.0 [8.3; 11.8] | 1.10 [0.99; 1.21] | 0.09 | ||
| Oronasal (%) | 216/650 (33.2) | 43/100 (43.0) | 173/550 (31.5) | 0.58 [0.37; 0.91] | 0.14 | ||
| Nasal (%) | 375/650 (57.7) | 47/100 (47.0) | 328/550 (59.6) | Ref | 0.07 | ||
| Nasal pillows (%) | 59/650 (9.1) | 10/100 (10.0) | 49/550 (8.91) | 0.70 [0.33; 1.48] | 0.83 | ||
| Heated humidifier | 386/650 (59.4) | 66/100 (66.0) | 320/550 (58.2) | 0.72 [0.46; 1.12] | 0.14 | ||
| Heated breathing tube | 22/650 (3.4) | 3/100 (3.0) | 19/550 (3.5) | 1.16 [0.34; 3.99] | 0.82 | ||
| 2013 ATS statement tested thresholds | |||||||
| Current AHIflow (> 10) | 23/650 (3.4) | 5/100 (5.0) | 17/550 (3.1) | 0.61 [0.22; 1.68] | 0.34 | ||
| ResMed Nasal large leaks (95th > 24 L) | 53/154 (34.4) | 10/22 (45.5) | 43/132 (32.6) | 0.58 [0.23; 1.45] | 0.24 | ||
| ResMed Facial large leaks (95th > 36 L) | 28/131 (21.4) | 8/23 (34.8) | 20/108 (18.5) | 0.43 [0.16; 1.14] | 0.09 | ||
| Philips leaks (> 1 h of large leaks) | 11/356 (3.1) | 1/55 (1.82) | 10/301 (3.32) | 1.86 [0.23; 14.8] | 0.56 | ||
| Fisher Paykel leaks (> 60 L/min) | 8/8 (100) | 0/8 (0) | 8/8 (100) | NA | |||
| VAS scores | |||||||
| Patient perceived leaks (VAS score) | 3 [1; 5] | 3.0 [1.0; 6.0] | 3.0 [0.0; 5.0] | 0.97 [0.91; 1.05] | 0.48 | ||
| Patient perceived mouth dryness (VAS score) | 3 [0; 7] | 5 [1; 8] | 3 [0; 7] | 0.93 [0.88; 0.99] | 0.019 | ||