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. 2019 Sep 11;9:12. doi: 10.1186/s13569-019-0122-5

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© The Author(s) 2019

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — Frequency of CDKN2A mutations per histologic sarcoma type in Foundation Medicine dataset (n = 7733). Copy number changes (orange) dominate the mutational landscape with infrequent occurrences of SNVs (green) and rearrangements (purple). The overall prevalence of CDKN2A mutations in sarcoma (left most bar) is 16.7% (n = 7733), with the highest mutated tumor being MPNST (60.7%, n = 262) followed by myxofibrosarcoma (29.3%, n = 140), and undifferentiated pleomorphic sarcoma (26.8%, n = 372)